Name: 4-Methylpyrazole
MF: C₄H₆N₂
CAS No.: 7554-65-6
EINECS: 231-445-0
4-Methylpyrazole is an important pyrazole compound. Due to its selective inhibitory effect on alcohol dehydrogenase, it has well-established applications in the pharmaceutical field. It is also used in coordination chemistry and other scientific research
Structure and Properties
4-Methylpyrazole acts as a competitive inhibitor of alcohol dehydrogenase, with a clear mechanism of action and well-defined targets. Structurally, the pyrazole ring provides coordination capability, allowing participation in the construction of metal complexes.
Pharmaceutical field:
Used as a raw material or research compound for drugs related to the treatment of methanol and ethylene glycol poisoning
Scientific research:
Used in coordination chemistry and complex studies to construct metal coordination systems
| Melting Point: | 13 °C |
| Boiling Point: | 99–100 °C / 6 mmHg (lit.) |
| Density: | 0.993 g/mL at 25 °C (lit.) |
| Vapor Pressure: | 7.136–87.85 Pa at 20–50 °C |
| Refractive Index: | n²⁰/D 1.495 (lit.) |
| Flash Point: | 205 °F |
| Solubility: | Soluble in water |
| Items | Specification | Results |
|---|---|---|
| Appearance | Colorless to light yellow liquid (solidifies below 15 °C) | Light yellow liquid (solidifies below 15 °C) |
| Assay (GC) | ≥98% | 99.70% |
Moisture Content (Karl Fischer) | ≤0.5% | 0.15% |
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