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1,3-Benzoxazine-2,4-(3H)-dione,Carsalam,Intermediate for SNAC
CAS: 2037-95-8
Carsalam,SNAC,Semaglutide synergist intermediate

Name:1,3-Benzoxazine-2,4-(3H)-dione

Cas:2037-95-8

EC:606-541-4

MF:C8H5NO3

Synonyms:Carsalam


Appearance:White powder

Assay:99%min

Melting point:228 oC

Not soluble in water


We have established unique environmental benign production route for Carsalam, getting rid of toxic substance use in the production process, current available capacity up to Tonnage level, produced in GMP facility.


Carsalam  is used to produce SNAC(Salcaprozate Sodium,Cas 203787-91-1) which is a synergist used to enhance the oral absorption of medications like GLP-1RA(Semaglutide etc),SNAC was developed by Emisphere in 1990s.


SNAC belongs to a class of compounds known as surfactants, which help increase the solubility of drugs in the gastrointestinal tract, thereby improving their bioavailability. This compound finds widespread applications in medical research and drug development, particularly for drugs with low oral bioavailability.  SNAC is drawing more attention due to the small molecule GLP-1RA(Liraglutide,semaglutide,dulaglutide,Albiglutide) becomes popular and eye-catching, It enhances the absorption and bioavailbility of GLP-1RA while reducing its degradation by enzymes. 


Semaglutide ,developed by Novo Nordisk, is one of the most famous one among the class, used to cure type II diabetes and have good potential for body weight control. 






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