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5-Amino-4,6-dichloro-2-methylpyrimidine
CAS: 39906-04-2
Moxonidine intermediate
MF:C5H5Cl2N3
MW:178.02

Purity: 98%+

Moxonidine, also known as Physiotens, is a highly selective imidazoline receptor agonist-Ⅰ by excitement ventrolateral medulla nucleus (RVLM)-Ⅰ type imidazoline receptor in the peripheral sympathetic nerve activity decreased. This receptor subtype is found in both the rostral ventro-lateral pressor and ventromedial depressor areas of the medulla oblongata.

Moxonidine therefore causes a decrease in sympathetic nervous system activity and, therefore, a decrease in blood pressure.


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